Promega Corporation

Trypsin/Lys-C Mix, Mass Spec Grade

Trypsin/Lys-C Mix, Mass Spec Grade, is a mixture of Trypsin Gold, Mass Spectrometry Grade, and rLys-C, Mass Spec Grade. The Trypsin/Lys-C Mix is designed to improve digestion of proteins or protein mixtures in solution.

Trypsin/Lys-C Mix is recommended for use in two applications, standard in-solution protein digestion and in-solution digestion of proteolytically resistant proteins. The first application is intended for users who would like to improve the overall proteolytic efficiency using standard digestion conditions. Digestion of proteolytically resistant proteins utilizes a specialized, two-step procedure, with...

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Trypsin/Lys-C Mix, Mass Spec Grade

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Trypsin/Lys-C Mix, Mass Spec Grade

 Components

  • Resuspension Buffer

    V181A1 x 500μl
  • Trypsin/Lys-C Mix, Mass Spec Grade

    V507A1 x 20μg
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  • This product can be added to a

  • Helix Freezer

This product is available through the Promega Helix onsite stocking program in a –20°C Helix Freezer. The program offers numerous convenient solutions to meet your lab's needs. Helix Freezers are available in two sizes: 5.7 cubic ft. or 9.7 cubic ft.


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20μg
- V5071 Please Enquire

Trypsin/Lys-C Mix, Mass Spec Grade

Close Window

Trypsin/Lys-C Mix, Mass Spec Grade

 Components

  • Resuspension Buffer

    V181A1 x 500μl
  • Trypsin/Lys-C Mix, Mass Spec Grade

    V507B1 x 100μg
Close Window
  • This product can be added to a

  • Helix Freezer

This product is available through the Promega Helix onsite stocking program in a –20°C Helix Freezer. The program offers numerous convenient solutions to meet your lab's needs. Helix Freezers are available in two sizes: 5.7 cubic ft. or 9.7 cubic ft.


Click here to learn more about the Helix Collection »


Already a Helix Customer?

Login to request to add this product to your Helix »


100μg
- V5072 Please Enquire

Trypsin/Lys-C Mix, Mass Spec Grade

Close Window

Trypsin/Lys-C Mix, Mass Spec Grade

 Components

  • Resuspension Buffer

    V181A1 x 500μl
  • Trypsin/Lys-C Mix, Mass Spec Grade

    V507A5 x 20μg
Close Window
  • This product can be added to a

  • Helix Freezer

This product is available through the Promega Helix onsite stocking program in a –20°C Helix Freezer. The program offers numerous convenient solutions to meet your lab's needs. Helix Freezers are available in two sizes: 5.7 cubic ft. or 9.7 cubic ft.


Click here to learn more about the Helix Collection »


Already a Helix Customer?

Login to request to add this product to your Helix »


100μg
(5 × 20µg)
- V5073 Please Enquire


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Storage Conditions

Store Trypsin/Lys-C Mix, Mass Spec Grade, at –30°C to –10°C.

For product intended use please see Patents & Disclaimers tab.

Figures

11477MA350x283Figure 1. Side-by-side comparison of trypsin and Trypsin/Lys-C digestion for missed cleavages (% of total cleavages).

All digests used overnight 37°C incubation.

Improved mass spec analysis of a poorly purified protein extract.Figure 2. Improved mass spec analysis of a poorly purified protein extract.

The extract contained a residual amount of methanol and chloroform, which inhibits trypsin, but not Trypsin/Lys-C Mix digestion.

Digestion of proteolytic-resistant proteins.Figure 3. Digestion of proteolytic-resistant proteins.

Trypsin/Lys-C Mix improves overall digestion due to Lys-C's tolerance to denaturing conditions.

Trypsin/Lys-C Mix improves overall digestion due to Lys-C's tolerance to denaturing conditions.

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Use Restrictions

V5071, V5072, V5073 For Research Use Only. Not for Use in Diagnostic Procedures.

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