DNA-Dependent Protein Kinase Peptide Substrate
Highly Specific Substrate for DNA-PK
- Supplied at 10mg/ml in water
- Km value for peptide is 760μM
Catalog Number:
Size
Catalog Number: V5671
DNA-Dependent Protein Kinase Peptide Substrate
DNA-Dependent Protein Kinase(DNA-PK)Peptide Substrateは配列Glu-Pro-Pro-Leu-Ser-Gln-Glu-Ala-Phe-Ala-Asp-Leu-Trp-Lys-LysのDNA-PKに対して高い特異性を有する基質です。そのペプチドのKm値は760μM。DNA-PKは核に存在するセリン/スレオニンプロテインキナーゼで、DNAによって活性化されると、腫瘍抑制因子p53、SV40large T抗原、いくつかの転写因子（例:SP1、OCT-1、c-Fosおよび血清応答因子）を含むDNA結合基質を活性化します。
特性:
- 濃度：10mg/ml（中性pHの水で供給）
- 分子量：1,759Da.
- ペプチド含量： ≥ 70% （FAB/MSによるペプチドの質量分析により検定）
- Lees-Miller, S.P. et al. (1992) Mol. Cell. Biol. 12, 5041–9.
Protocols
No protocols available
Specifications
Catalog Number:
選択製品の構成品内容
| Item | Part # | Size |
|---|---|---|
|
DNA-Dependent Protein Kinase Substrate |
V567A | 1 × 1mg |
SDS
Search for SDS分析証明書
使用制限
For Research Use Only. Not for Use in Diagnostic Procedures.保存条件
Store at –20°C.
Resources
No related resources available
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