Measure every Fc effector mechanism: Simplified, integrated workflows for characterizing antibody Fc effector activity. Explore tools from discovery through lot release.

ADCC Reporter Bioassay, V Variant

Part Numbers: G7015, G7014, G7010, G7016, G7013, G7018, G7102, GA1130

customize-this-small

Fc エフェクター機能測定のための作用機序ベースの発光バイオアッセイ

  • 3種類のキットフォーマット:
  • コンプリート - アッセイ開始に必要な全てが揃ったキット
  • コア - 利用者が準備する抗体および標的細胞以外が含まれるキット
  • ターゲット - コアキットとともに使用するコントロール
  • コンプリートとターゲットキットにはRaji または WIL2-S target cells が含まれる2種類のタイプ

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選択製品のカタログ番号: G7015

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This product is discontinued
This product is available under our Early Access program - Learn More
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ADCC Reporter Bioassay, V Variant
Complete Kit, Raji/1 each
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不確実でバラつく "プライマリー細胞ベース" のADCC アッセイ はもういらない

Fc受容体を介した抗体依存性細胞傷害(ADCC:Antibody-dependent cell-mediated cytotoxicity)は抗体による罹患細胞を標的とした排除のために重要な作用機序です。従来の方法では細胞表面にFc受容体を発現している末梢血単核球(PBMCs)や精製したナチュラルキラー細胞(NK)[初代細胞]をドナーから採取してADCC測定に使用していました。関連する抗体のFc領域が標的とする罹患細胞に結合すると、Fc受容体がエフェクター細胞内へのシグナルに変換して標的細胞を排除することになります。これらの初代細胞をベースとしたアッセイは、ドナーの違いや細胞培養の要件などにより大きなバラツキがあることが問題でした。

ADCC Reporter Bioassayは生物学的関連性があり、特定のADCC作用機序をベースとしており、初代細胞をベースとしたアッセイで見られる複雑なワークフローやバラツキもありません。特に初代細胞であるドナーのPBMCやNK細胞をFcγRIIIa(高親和性V158または低親和性F158受容体)およびNFAT-誘導性ルシフェラーゼを安定に発現するJurkat細胞に置き換えられていることが特長的です。また、ADCC Reporter Bioassayは従来のLDH放出ADCCバイオアッセイと同等の抗体活性ランキングを示すことは重要です。さらに、このバイオアッセイはFcエフェクター機能における抗体のグリコシル化の影響を定量する場合にも使用することができます。

ADCC Bioassay Effector Cells, Propagation ModelはADCC Bioassay Effector Cellsは増やしてバンキングすることが可能です。ADCC Bioassay Effector Cells,Propagation Modelを使用する際はBio-Glo™ Luciferase Assay Systemが必要です。製品には 2つのバイアル付属しており、1バイアルあたり細胞が0.65ml(2×107 個細胞/ml)分注されています。片方のバイアルを溶かして増殖させ、細胞バンクをつくる場合は凍結させてください。残りのバイアルはバックアップとして保管してください。

  • ADCC作用機序の決定または確認(またはその欠如)
  • 抗体の力価および安定性の測定
  • ADCCにおける抗体のグリコシル化およびアフコシル化の影響を決定
  • 抗体のスクリーニング

【ライセンス】ADCC Bioassay   【Q&A】ADCC Reporter Bioassay

【かわら版】驚きの再現性 : 発光レポーターを利用した ADCC アッセイ
【かわら版】ADCC 発光レポーターバイオアッセイを用いた 抗 TNF 抗体医薬品および抗ウイルスワクチンの評価

ワークフロー

Standard bioassay workflow with cultured cells
Improved bioassay workflow with thaw-and-use cells

標準化された試薬による改善点

  • 製品に含まれる細胞を融解して使用するだけなので、従来法よりも飛躍的に時間と労力が低減し、バラつきも減少
  • キットは標準化フォーマットとして必要な全ての試薬を供給
  • ハイスループットなワークフローにも容易に適応

アッセイ原理

この Fc Effector Reporter Bioassay は従来のプライマリー細胞ベースのアッセイとは異なる検出法を採用:エフェクター細胞内で FcγR およびNFATを介したルシフェラーゼの活性化を検出します。プライマリー細胞は ヒト FcγRIIIa V158 および NFAT-誘導ルシフェラーゼを安定に発現する Jurkat 細胞株に置き換えられます。

10338MA-W

発光アッセイによる Fc エフェクター活性のモニタリング

標的抗体がターゲット細胞に結合し、Fc 領域も ADCC Bioassay Effector Cellsに結合すると、この細胞内に発現する FcγRIIIa を介してシグナルが細胞内に伝わりNFAT応答配列により発現制御された定量の容易なルシフェラーゼの活性として測定される。

アッセイパフォーマンスデータ

正確度 (accuracy) と 精度 (precision) はバイオアッセイやバイオロジックス開発において非常に重要です。ADCC Reporter Bioassay は正確度と 精度を兼ね備えたアッセイです(正確度とは標的または参照値に対してどれほど近かったかという度合いであり、精度は再現性の度合いです)。

32454752-data-target-combined

製品フォーマット

Complete Kits

  • IADCC Bioassayエフェクター細胞、ターゲット細胞、コントロール抗体、培地 および アッセイ試薬で構成
  • スターターキットとして推奨
  • RajiまたはWIL2-Sの2つのターゲット細胞を用意

Core Kits

  • ADCC Bioassayエフェクター細胞、培地およびアッセイ試薬で構成
  • ルーチン実験用として推奨(使用する抗体、ターゲット細胞が確定している方)
  • 1Xと5Xのサイズを用意

Target Kits

  • ADCC Bioassayターゲット細胞、コントロール抗体で構成
  • すべてのFc Effector Bioassay Core Kitsのコントロールとしての使用を推奨
  • RajiまたはWIL2-Sの2つのターゲット細胞を用意

この他のフォーマットのオプションについては こちら.

32454665-ADCC-product-format

ADCC Bioassay Effector Cells, Propagation Model

  • Includes ADCC Bioassay Effector Cells (CPM); these are cryopreserved cells that can be thawed, propagated and banked for long-term use. Product includes two vials at 2 × 107 cells/ml and 1.0ml/vial. One vial should be thawed, propagated and cells frozen to create a cell bank. The remaining vial should be reserved as backup.
  • Bio-Glo™ Luciferase Assay System is the required reagent for use with ADCC Bioassay Effector Cells, Propagation Model. 

Control Antibody, Anti-CD20

  • Intended for use as a control antibody with the ADCC Bioassay.

For additional format options please enquire.

ADCC Reporter Bioassay Precision, Accuracy and Linearity

WIL2-S Target Cells

Parameter Results
Accuracy % Expected Relative Potency % Recovery
50 97.7
75 88.5
125 98.4
150 98.4
Repeatability (% CV) 100% (Reference) 5.0%
Intermediate Precision (% CV)   7.3%
Linearity (r2)   0.995 (50–200% range)
Linearity (y = mx + b)   y = 1.016x – 0.052

Raji Target Cells

Parameter Results
Accuracy % Expected Relative Potency % Recovery
50 101.0
75 101.2
150 93.8
200 96.7
Repeatability (% CV) 100% (Reference) 9.1
Intermediate Precision (% CV)   3.0
Linearity (r2)   0.997 (50–200% range)
Linearity (y = mx + b)   y = 0.922x + 5
ADCC activity is a major mode of action of therapeutic monoclonal antibodies and is generally determined using a cell-based assay with primary PBMCs. ADCC Reporter Bioassay allows to measure the potency of an antibody without the constraint of PBMC donors’ variability and with a high level of performance. This assay was successfully validated and implemented in our company for batch release testing.

Dr. Fabian Vandermeers, Sr R&D Technical Leader, Quality Assistance S.A.

製品仕様

You are viewing: G7015 Change Configuration

選択製品の構成品内容

Item Part # Size Concentration

ADCC Bioassay Effector Cells

G701A 1 × 1 vial

ADCC Bioassay Target Cells (Raji)

G870A 1 × 0.55ml

Low IgG Serum

G711A 1 × 4ml

Control Ab, Anti-CD20

GA113A 1 × 5μg 0.5mg/ml

RPMI 1640 Medium

G708A 1 × 36ml

Bio-Glo™ Luciferase Assay Buffer

G719A 1 × 10ml

Bio-Glo™ Luciferase Assay Substrate

G720A 1 × 1 vial

分析証明書

Search by lot number

保存条件

Please see the Protocol for detailed storage instructions.

パテントおよび免責条項

NOT FOR MEDICAL DIAGNOSTIC USE. FOR IN VITRO USE ONLY. BY USE OF THIS PRODUCT, RECIPIENT AGREES TO BE BOUND BY THE TERMS OF THIS LIMITED USE STATEMENT. If the recipient is not willing to accept the conditions of this limited use statement, and the product is unused, Promega will accept return of the unused product and provide the recipient with a full refund.
This product may not be further sold or transferred by the recipient and may be used only by the recipient, and then only for (1) research use, (2) drug discovery and development of biologic drugs, (3) quality assurance testing of biologic drugs, and (4) product release assays for biologic drugs. No other commercial use is allowed. "Commercial use” means any and all uses of this product by recipient for monetary or other consideration, including providing a service, information or data to unaffiliated third parties, and resale of this product for any use. Recipient has no right to propagate, modify, derivatize, genetically engineer or otherwise create variations of the Effector Cells or the luciferase gene stably transfected within the Effector Cells. In addition, recipient must use Bio-Glo™ Luciferase Assay System purchased from Promega Corporation for all determinations of luminescence activity of this product, or contact Promega to obtain a license for use of this product with reagents other than Promega’s. PROMEGA MAKES NO REPRESENTATIONS OR WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING AS TO MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE WITH REGARDS TO THIS PRODUCT. The terms of this agreement shall be governed under the laws of the State of Wisconsin, USA.

NOT FOR MEDICAL DIAGNOSTIC USE. FOR IN VITRO USE ONLY. BY USE OF THIS PRODUCT, RECIPIENT AGREES TO BE BOUND BY THE TERMS OF THIS LIMITED USE STATEMENT. If the recipient is not willing to accept the conditions of this limited use statement, and the product is unused, Promega will accept return of the unused product and provide the recipient with a full refund.
This product may not be further sold or transferred by the recipient and may be used only by the recipient, and then only for (1) research use, (2) drug discovery and development of biologic drugs, (3) quality assurance testing of biologic drugs, and (4) product release assays for biologic drugs. No other commercial use is allowed. “Commercial use” means any and all uses of this product by recipient for monetary or other consideration, including providing a service, information or data to unaffiliated third parties, and resale of this product for any use. Recipient has no right to propagate, modify, derivatize, genetically engineer or otherwise create variations of the Target Cells. In addition, recipient must use Bio-Glo™ Luciferase Assay System purchased from Promega Corporation for all luminescence assays using this product, or contact Promega to obtain a license for use of this product with reagents other than Promega’s. PROMEGA MAKES NO REPRESENTATIONS OR WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING AS TO MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE WITH REGARDS TO THIS PRODUCT. The terms of this agreement shall be governed under the laws of the State of Wisconsin, USA.

U.S. Pat. No. 10,077,244 and other patents.

Licensed from Lonza Cologne GmbH under U.S. Pat. Nos. 7,700,357, 8,192,990 and 8,003,389, European Pat. Nos. 1297119, 1522587, 1607484 and 1741778 and other pending and issued patents.

製品仕様

You are viewing: G7014 Change Configuration

選択製品の構成品内容

Item Part # Size Concentration

ADCC Bioassay Effector Cells

G701A 1 × 1 vial

ADCC Bioassay Target Cells (WIL2-S)

G727A 1 × 0.55ml

Low IgG Serum

G711A 1 × 4ml

Control Ab, Anti-CD20

GA113A 1 × 5μg 0.5mg/ml

RPMI 1640 Medium

G708A 1 × 36ml

Bio-Glo™ Luciferase Assay Buffer

G719A 1 × 10ml

Bio-Glo™ Luciferase Assay Substrate

G720A 1 × 1 vial

分析証明書

Search by lot number

保存条件

Please see the Protocol for detailed storage instructions.

パテントおよび免責条項

NOT FOR MEDICAL DIAGNOSTIC USE. FOR IN VITRO USE ONLY. BY USE OF THIS PRODUCT, RECIPIENT AGREES TO BE BOUND BY THE TERMS OF THIS LIMITED USE STATEMENT. If the recipient is not willing to accept the conditions of this limited use statement, and the product is unused, Promega will accept return of the unused product and provide the recipient with a full refund.
This product may not be further sold or transferred by the recipient and may be used only by the recipient, and then only for (1) research use, (2) drug discovery and development of biologic drugs, (3) quality assurance testing of biologic drugs, and (4) product release assays for biologic drugs. No other commercial use is allowed. "Commercial use” means any and all uses of this product by recipient for monetary or other consideration, including providing a service, information or data to unaffiliated third parties, and resale of this product for any use. Recipient has no right to propagate, modify, derivatize, genetically engineer or otherwise create variations of the Effector Cells or the luciferase gene stably transfected within the Effector Cells. In addition, recipient must use Bio-Glo™ Luciferase Assay System purchased from Promega Corporation for all determinations of luminescence activity of this product, or contact Promega to obtain a license for use of this product with reagents other than Promega’s. PROMEGA MAKES NO REPRESENTATIONS OR WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING AS TO MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE WITH REGARDS TO THIS PRODUCT. The terms of this agreement shall be governed under the laws of the State of Wisconsin, USA.

NOT FOR MEDICAL DIAGNOSTIC USE. FOR IN VITRO USE ONLY. BY USE OF THIS PRODUCT, RECIPIENT AGREES TO BE BOUND BY THE TERMS OF THIS LIMITED USE STATEMENT. If the recipient is not willing to accept the conditions of this limited use statement, and the product is unused, Promega will accept return of the unused product and provide the recipient with a full refund.
This product may not be further sold or transferred by the recipient and may be used only by the recipient, and then only for (1) research use, (2) drug discovery and development of biologic drugs, (3) quality assurance testing of biologic drugs, and (4) product release assays for biologic drugs. No other commercial use is allowed. “Commercial use” means any and all uses of this product by recipient for monetary or other consideration, including providing a service, information or data to unaffiliated third parties, and resale of this product for any use. Recipient has no right to propagate, modify, derivatize, genetically engineer or otherwise create variations of the Target Cells. In addition, recipient must use Bio-Glo™ Luciferase Assay System purchased from Promega Corporation for all luminescence assays using this product, or contact Promega to obtain a license for use of this product with reagents other than Promega’s. PROMEGA MAKES NO REPRESENTATIONS OR WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING AS TO MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE WITH REGARDS TO THIS PRODUCT. The terms of this agreement shall be governed under the laws of the State of Wisconsin, USA.

U.S. Pat. No. 10,077,244 and other patents.

Licensed from Lonza Cologne GmbH under U.S. Pat. Nos. 7,700,357, 8,192,990 and 8,003,389, European Pat. Nos. 1297119, 1522587, 1607484 and 1741778 and other pending and issued patents.

製品仕様

You are viewing: G7010 Change Configuration

選択製品の構成品内容

Item Part # Size

ADCC Bioassay Effector Cells

G701A 1 × 1 vial

Low IgG Serum

G711A 1 × 4ml

RPMI 1640 Medium

G708A 1 × 36ml

Bio-Glo™ Luciferase Assay Buffer

G719A 1 × 10ml

Bio-Glo™ Luciferase Assay Substrate

G720A 1 × 1 vial

分析証明書

Search by lot number

保存条件

Please see the Protocol for detailed storage instructions.

パテントおよび免責条項

NOT FOR MEDICAL DIAGNOSTIC USE. FOR IN VITRO USE ONLY. BY USE OF THIS PRODUCT, RECIPIENT AGREES TO BE BOUND BY THE TERMS OF THIS LIMITED USE STATEMENT. If the recipient is not willing to accept the conditions of this limited use statement, and the product is unused, Promega will accept return of the unused product and provide the recipient with a full refund.
This product may not be further sold or transferred by the recipient and may be used only by the recipient, and then only for (1) research use, (2) drug discovery and development of biologic drugs, (3) quality assurance testing of biologic drugs, and (4) product release assays for biologic drugs. No other commercial use is allowed. "Commercial use” means any and all uses of this product by recipient for monetary or other consideration, including providing a service, information or data to unaffiliated third parties, and resale of this product for any use. Recipient has no right to propagate, modify, derivatize, genetically engineer or otherwise create variations of the Effector Cells or the luciferase gene stably transfected within the Effector Cells. In addition, recipient must use Bio-Glo™ Luciferase Assay System purchased from Promega Corporation for all determinations of luminescence activity of this product, or contact Promega to obtain a license for use of this product with reagents other than Promega’s. PROMEGA MAKES NO REPRESENTATIONS OR WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING AS TO MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE WITH REGARDS TO THIS PRODUCT. The terms of this agreement shall be governed under the laws of the State of Wisconsin, USA.

U.S. Pat. No. 10,077,244 and other patents.

Licensed from Lonza Cologne GmbH under U.S. Pat. Nos. 7,700,357, 8,192,990 and 8,003,389, European Pat. Nos. 1297119, 1522587, 1607484 and 1741778 and other pending and issued patents.

製品仕様

You are viewing: G7016 Change Configuration

選択製品の構成品内容

Item Part # Size Concentration

ADCC Bioassay Target Cells (Raji)

G870A 1 × 0.55ml

Control Ab, Anti-CD20

GA113A 1 × 5μg 0.5mg/ml

分析証明書

Search by lot number

保存条件

Please see the Protocol for detailed storage instructions.

パテントおよび免責条項

NOT FOR MEDICAL DIAGNOSTIC USE. FOR IN VITRO USE ONLY. BY USE OF THIS PRODUCT, RECIPIENT AGREES TO BE BOUND BY THE TERMS OF THIS LIMITED USE STATEMENT. If the recipient is not willing to accept the conditions of this limited use statement, and the product is unused, Promega will accept return of the unused product and provide the recipient with a full refund.
This product may not be further sold or transferred by the recipient and may be used only by the recipient, and then only for (1) research use, (2) drug discovery and development of biologic drugs, (3) quality assurance testing of biologic drugs, and (4) product release assays for biologic drugs. No other commercial use is allowed. “Commercial use” means any and all uses of this product by recipient for monetary or other consideration, including providing a service, information or data to unaffiliated third parties, and resale of this product for any use. Recipient has no right to propagate, modify, derivatize, genetically engineer or otherwise create variations of the Target Cells. In addition, recipient must use Bio-Glo™ Luciferase Assay System purchased from Promega Corporation for all luminescence assays using this product, or contact Promega to obtain a license for use of this product with reagents other than Promega’s. PROMEGA MAKES NO REPRESENTATIONS OR WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING AS TO MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE WITH REGARDS TO THIS PRODUCT. The terms of this agreement shall be governed under the laws of the State of Wisconsin, USA.

U.S. Pat. No. 10,077,244 and other patents.

製品仕様

You are viewing: G7013 Change Configuration

選択製品の構成品内容

Item Part # Size Concentration

ADCC Bioassay Target Cells (WIL2-S)

G727A 1 × 0.55ml

Control Ab, Anti-CD20

GA113A 1 × 5μg 0.5mg/ml

分析証明書

Search by lot number

保存条件

Please see the Protocol for detailed storage instructions.

パテントおよび免責条項

NOT FOR MEDICAL DIAGNOSTIC USE. FOR IN VITRO USE ONLY. BY USE OF THIS PRODUCT, RECIPIENT AGREES TO BE BOUND BY THE TERMS OF THIS LIMITED USE STATEMENT. If the recipient is not willing to accept the conditions of this limited use statement, and the product is unused, Promega will accept return of the unused product and provide the recipient with a full refund.
This product may not be further sold or transferred by the recipient and may be used only by the recipient, and then only for (1) research use, (2) drug discovery and development of biologic drugs, (3) quality assurance testing of biologic drugs, and (4) product release assays for biologic drugs. No other commercial use is allowed. “Commercial use” means any and all uses of this product by recipient for monetary or other consideration, including providing a service, information or data to unaffiliated third parties, and resale of this product for any use. Recipient has no right to propagate, modify, derivatize, genetically engineer or otherwise create variations of the Target Cells. In addition, recipient must use Bio-Glo™ Luciferase Assay System purchased from Promega Corporation for all luminescence assays using this product, or contact Promega to obtain a license for use of this product with reagents other than Promega’s. PROMEGA MAKES NO REPRESENTATIONS OR WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING AS TO MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE WITH REGARDS TO THIS PRODUCT. The terms of this agreement shall be governed under the laws of the State of Wisconsin, USA.

U.S. Pat. No. 10,077,244 and other patents.

製品仕様

You are viewing: G7018 Change Configuration

選択製品の構成品内容

Item Part # Size

ADCC Bioassay Effector Cells

G701A 5 × 1 vial

Low IgG Serum

G711A 5 × 4ml

RPMI 1640 Medium

G708A 5 × 36ml

Bio-Glo™ Luciferase Assay Buffer

G719A 5 × 10ml

Bio-Glo™ Luciferase Assay Substrate

G720A 5 × 1 vial

分析証明書

Search by lot number

保存条件

Please see the Protocol for detailed storage instructions.

パテントおよび免責条項

NOT FOR MEDICAL DIAGNOSTIC USE. FOR IN VITRO USE ONLY. BY USE OF THIS PRODUCT, RECIPIENT AGREES TO BE BOUND BY THE TERMS OF THIS LIMITED USE STATEMENT. If the recipient is not willing to accept the conditions of this limited use statement, and the product is unused, Promega will accept return of the unused product and provide the recipient with a full refund.
This product may not be further sold or transferred by the recipient and may be used only by the recipient, and then only for (1) research use, (2) drug discovery and development of biologic drugs, (3) quality assurance testing of biologic drugs, and (4) product release assays for biologic drugs. No other commercial use is allowed. "Commercial use” means any and all uses of this product by recipient for monetary or other consideration, including providing a service, information or data to unaffiliated third parties, and resale of this product for any use. Recipient has no right to propagate, modify, derivatize, genetically engineer or otherwise create variations of the Effector Cells or the luciferase gene stably transfected within the Effector Cells. In addition, recipient must use Bio-Glo™ Luciferase Assay System purchased from Promega Corporation for all determinations of luminescence activity of this product, or contact Promega to obtain a license for use of this product with reagents other than Promega’s. PROMEGA MAKES NO REPRESENTATIONS OR WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING AS TO MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE WITH REGARDS TO THIS PRODUCT. The terms of this agreement shall be governed under the laws of the State of Wisconsin, USA.

U.S. Pat. No. 10,077,244 and other patents.

Licensed from Lonza Cologne GmbH under U.S. Pat. Nos. 7,700,357, 8,192,990 and 8,003,389, European Pat. Nos. 1297119, 1522587, 1607484 and 1741778 and other pending and issued patents.

製品仕様

You are viewing: G7102 Change Configuration

選択製品の構成品内容

Item Part # Size

ADCC Bioassay Effector Cells (CPM)

G701B 2 × 1.0ml

分析証明書

Search by lot number

使用制限

Not For Medical Diagnostic Use.

保存条件

XX

Please see the Protocol for detailed storage instructions.

パテントおよび免責条項

NOT FOR MEDICAL DIAGNOSTIC USE. FOR IN VITRO USE ONLY. BY USE OF THIS PRODUCT, RECIPIENT AGREES TO BE BOUND BY THE TERMS OF THIS LIMITED USE STATEMENT. If the recipient is not willing to accept the conditions of this limited use statement, and the product is unused, Promega will accept return of the unused product and provide the recipient with a full refund.
This product may not be further sold or transferred by the recipient and may be used only by the recipient, and then only for (1) research use, (2) drug discovery and development of biologic drugs, (3) quality assurance testing of biologic drugs, and (4) product release assays for biologic drugs. No other commercial use is allowed. "Commercial use" means any and all uses of this product by recipient for monetary or other consideration, including providing a service, information or data to unaffiliated third parties, and resale of this product for any use. Recipient has no right to modify, derivatize, genetically engineer or otherwise create variations of the Effector Cells or the luciferase gene stably transfected within the Effector Cells, except that recipient may propagate and store Effector Cells for use in Antibody-Dependent Cell-Mediated Cytotoxicity assays. In addition, recipient must use Bio-Glo™ Luciferase Assay System purchased from Promega Corporation for all determinations of luminescence activity of this product, or contact Promega to obtain a license for use of this product with reagents other than Promega's. PROMEGA MAKES NO REPRESENTATIONS OR WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING AS TO MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE WITH REGARDS TO THIS PRODUCT. The terms of this agreement shall be governed under the laws of the State of Wisconsin, USA.

Licensed from Lonza Cologne GmbH under U.S. Pat. Nos. 7,700,357, 8,192,990 and 8,003,389, European Pat. Nos. 1297119, 1522587, 1607484 and 1741778 and other pending and issued patents.

製品仕様

You are viewing: GA1130 Change Configuration

選択製品の構成品内容

Item Part # Size Concentration

Control Ab, Anti-CD20

GA113A 1 × 5μg 0.5mg/ml

分析証明書

Search by lot number

使用制限

Not For Medical Diagnostic Use.

保存条件

BB

Please see the Protocol for detailed storage instructions.

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